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septembre 2013

  • 20 septCircuit mechanisms regulating adult neural stem cells and neurogenesis

    20 sept 2013
    Séminaires/Colloques

    By Hongjun Song, Johns Hopkins University
     

    Circuit mechanisms regulating adult neural stem cells and neurogenesis. 

     Adult neurogenesis arises from neural stem cells within specialized niches. Neuronal activity and experience, presumably acting on this local niche, regulate multiple stages of adult neurogenesis, from neural stem cell activation, neural progenitor proliferation to new neuron maturation, synaptic integration and survival. I will present our recent studies using slice electrophysiology, immunohistology, genetic lineage tracing and manipulation and optogenetics to identify a novel niche mechanism involving parvalbumin-expressing interneurons that couples local circuit activity to diametric regulation of two critical early sequential phases of adult hippocampal neurogenesis.

     

    Friday, September 20th, 2013 at 11:30 am
     Salle des Thèses (5th floor Jacob building)
     Centre Universitaire des Saints-Péres
     45 rue des Saints-Péres, 75006 Paris

     

    Retrouvez la programmation des séminaires à venir sur le site de l'UFR des Siences Fondametales et Biomédicales