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novembre 2012

  • 30 novThe Human Intestinal Microbiota in Metabolic Disorders

    30 nov 2012

    Joël DORE, invité par Michel ARTHUR

    INRA Jouy-en-Josas – UMR 1319 – « Ecologie et Physiologie du système digestif »



    The human intestinal tract harbours a complex microbial ecosystem which plays a key role in nutrition and health. Current investigations into the human faecal metagenome are delivering an unprecedented view of the intestinal microbiota and refining a suspected link with human metabolism. Specific traits of the microbiota allow a stratification of the human population with a potential to predict the response to dietary restriction in obesity. We are still quite far from delivering causal inter-relations between features of the microbiota and metabolic status of the host but current observations converge towards a general model with physiopathological relevance and functional metagenomics is expected to deliver a fine understanding of key  microbe-cell crosstalk mechanisms at play.


    Lieu : Centre de Recherche des Cordeliers, 15 rue de l’École de Médecine, Paris 75006, dans l’amphithéâtre BILSKI-PASQUIER à 12h